How to get stem cells?
It´s obtained from the umbilical cord blood, these dedicated cells should be frozen and stored in a special bank. The value of cord blood is in biologically active stem cells and so it is well for the needs of cell therapy and transplantation.
Everyone who wants to get the umbilical cord blood can go in the bank of donor blood. However, it’ s very difficult to find a suitable blood: it has to comply with the major antigenic system; otherwise, the patient can get rejection reaction. On the other way, you can get your own blood after birth and it always will be available for transplantation. The procedure of cord blood storage is well developed and it’s available on a contract basis for any parents.
What value of umbilical cord?
The umbilical cord has a huge reserve of hematopoietic stem cells that are the cells-progenitors of blood. They are available for transplantation when your own blood formation is broken: in leukemia, serious immune system disorders, and other diseases. Those who oppose cord blood storage have noticed that such pathologies are rare. In the other hand, the stem cells can be used more broadly. In any case, already now we’ve thousands of successful cord blood transplants that have saved the life of patients with incurable diseases.
The umbilical cord blood is not the only one source of hematopoietic cells, but it has a big number of advantages: easy and safe receipt, youth, and therefore a high functional activity of stem cells and immunological compatibility.
So other family members can use newborn cord blood for treatment. It has a mark about successful transplantation of blood to the parents, grandparents and even cousins. However, children from one large family have more chance to be compatible.
Every parent has their own decision about banking cord blood depending on their financial situation and necessity. First, you need to know that children with the predisposition to the hematopoietic diseases need to get cord blood of cousin and ethnic minorities because it is difficult to find a compatible donor for them.
How does cord blood banking work?
After the birth of the baby, the nurse secures and crosses the cord. Then she uses a sterile solution for the maternal end of the umbilical cord and with a needle.
she gets blood from the umbilical vein in a special sterile container with an anticoagulant. Cord blood is usually not too much, about 80 ml, so it’s sensible to remove all available blood from the placenta.
The procedure is painless and takes a few minutes. You can have it during normal childbirth and cesarean section. Moreover, it’s technologically possible to collect umbilical cord blood of each child in multiple pregnancies.
How to get stem cells?
In one day after collecting the sample, it must get into the bank. Before banking, it goes through a complete process. To get concentrate on stem cells you should test the sample on infection, the blood group, and Rh factor. The special device removes excess plasma and red blood cells. Test of the concentration under the microscope helps to detect cell viability. The next step is solidification, which should not lead to cell death. Therefore, a cryoprotectant protects cells from the formation of sharp ice crystals. Then concentrate stays frozen to -90 ° C in quarantine storage (vapors of liquid nitrogen, -150 ° C) until the results of all tests. Finally, after 20 days samples go to a permanent storage (liquid nitrogen, -196 ° C).
At the output, there are 5 to 7 vials of concentrate. In addition to the main tube, there are a few tubes-satellites. They contain the minimum amount of plasma and cells for analysis. For example, if the blood owner wants to use it for his relative and it is necessary to check it for compatibility, there is no need to defrost the basic sample. It will be enough to take the tube-satellite.
What is the process of banking stem cells?
Cord blood cells are stored in special containers with liquid nitrogen in a separate room, which is located deep underground. The special automated system controls low temperature and the level of liquid nitrogen. It will work even without central electric power. Cord blood bank keeps protection in day and night.
There’s no doubt that they save their properties for 15-17 years. In theory, all the frozen cells can be stored indefinitely.
Who is the owner of the stem cells?
Parents or to the person who is in the storage contract are the owners of the cord blood cells reserve before the adult age of a child.
How much does cord blood banking cost?
For all these processes of cord blood cells, you have to pay about ranges from about $1,200 to $5,000, plus annual storage costs of about $90 to $180. More details of price comparations: https://www.americordblood.com/pricing/comparison-chart/
What should you do if you want to save the cord blood?
At any pregnancy stage, you need to come to the cord blood bank to be tested for the infection and then to sign a contract. Then, the bank’s employees must deliver a nominal set with the unique barcode in a hospital, to warn the doctor and nurse to provide collection and delivery of blood to the bank, where the blood will provide stem cells.
It doesn’t matter if childbirth is a natural or cesarean section, if the woman is in the nearest hospital it is enough to call in the bank in any daytime to report about the location and bank employees will warn the doctors.